Dicarboxylic acids and derivatives
Apexbio Technology LLC CUDC-101 1012054-59-9 50mg
CUDC-101 (CAS 1012054-59-9) is a multitargeted small molecule inhibitor that concurrently targets epidermal growth factor receptor (EGFR) HER2 and class I and II histone deacetylases (HDACs) By inhibiting EGFR and HER2 kinases directly and simultaneously blocking HDAC activity CUDC-101 downregulates multiple oncogenic signaling pathways including those mediated by Akt HER3 and MET Preclinical assessments demonstrate that CUDC-101 inhibits growth of diverse tumor cell lines and xenograft models notably including those resistant to EGFR-targeted agents such as lapatinib and erlotinib These characteristics render CUDC-101 valuable for oncology research and drug resistance studies
Medchemexpress LLC Lauroyl-L-carnitine (chloride) | 6919-91-1 | 98.1% | 25 MG
Lauroyl-L-carnitine chloride is an orally active metabolite. It significantly reverses the decrease in its target gene IL-10 and alleviates Crohn's-like colitis.
- Orally active metabolite
- Reverses decrease in IL-10 gene
- Alleviates Crohn's-like colitis
- Purity: 98.14%
Medchemexpress LLC Vnt-101 | 2894060-67-2 | 456.41 | C21H23F3N2O6 | 10 MG
VNT-101 is a small-molecule, orally active inhibitor of influenza A virus nucleoprotein (NP) oligomerization. It disrupts NP-NP protein-protein interactions to destabilize the viral ribonucleoprotein complex and has been used in vitro and in vivo to study antiviral activity across multiple influenza A subtypes.
- Disrupts nucleoprotein oligomerization to inhibit viral replication.
- Orally bioavailable small molecule suitable for in vivo studies.
- Demonstrated activity against multiple influenza A subtypes.
- Molecular weight 456.41 and molecular formula C21H23F3N2O6.
- CAS number 2894060-67-2 for substance identification.
- Supplied as a solid for research use with supporting characterization data.
TARGETMOL CHEMICALS INC PKUMDL-LC-101-D04 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4) a regulator of iron death. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 uM in a cell-free assay and at a concentration of 61 uM in wild-type but not Gpx4-/- mouse embryonic fibroblast (MEF) extracts.PKUMDL-LC-101-D04 (200 uM) reduced cholesterol peroxide-induced MEF death. purity: 98%
Medchemexpress LLC VH 101, acid | 2408341-97-7 | >98.8% | C28H35FN4O6S | 50 MG
VH 101, acid | 2408341-97-7 | >98.8% | C28H35FN4O6S | 50 MG
Medchemexpress LLC Pigment Yellow 101 | 2387-03-3 | 98.1% | 5 MG
Pigment Yellow 101 is a yellow bis-azomethine pigment with excitation/emission at 411 nm/512 nm. It exhibits solid-state fluorescence and is available as a commercial colorant. This product is for research use only and not sold to patients.
- Yellow bis-azomethine pigment
- Exhibits solid-state fluorescence
- Excitation/emission: 411 nm/512 nm
- Available as a commercial colorant
Carbamide Peroxide, Spectrum™ Chemical
CAS: 124-43-6